Once upon a time, migrating peoples headed from the North American continent south, using a long trail that wound through Arizona on down Mexico way. It only takes a short walk to cross the border from Nogales, Arizona to Nogales, Mexico, but the ancient footpath was long ago replaced by asphalt.

This border city is located at the top of one of Mexico's major highway systems and provides access to the Baja Peninsula via ferry from Guaymas.

Day trippers over from the United States visit Nogales to buy pharmaceuticals, bargain for souvenirs and sample Mexican fare before making the trip back across the border. Visitors in transit can get an introduction to Mexican-style markets before venturing off to enjoy the state of Sonora.

Stop in at the Pimeria Alta Historical Society Museum on the Arizona side of Nogales for an introduction to area history.

Nogales is 244 miles north of Guaymas and 175 miles from Hermosillo.